Contraindicated (one)pentobarbital decreases amounts of vandetanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent coadministration with strong CYP3A4 inducers; these medicine lower publicity to vandetanib by as many as forty%.pentobarbital will lower the extent or result of stiripentol by impacting hepatic/inte
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